2-Ethyl-6-methylisonicotinic acid → 2-Ethyl-6-methyl-isonicotinic acid hydrazide

HRID 1908849Notes

Reaction equation

HRID 1908849 reaction equation
Cl.[CH3:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([CH3:13])[N:12]=1)[C:6]([NH:8][NH2:9])=[O:7].[CH2:14](C1C=C(C=C(C)N=1)C(O)=O)C>>[CH2:13]([C:11]1[CH:10]=[C:5]([CH:4]=[C:3]([CH3:2])[N:12]=1)[C:6]([NH:8][NH2:9])=[O:7])[CH3:14]

Participants

3

Reactant 2

HCID 584180972-Ethyl-6-methylisonicotinic acidHCID 670271882,6-Dimethyl-isonicotinic acid hydrazide hydrochloride

Product 1

HCID 670269272-Ethyl-6-methyl-isonicotinic acid hydrazide

Procedure

The title compound is prepared in analogy to 2,6-dimethyl-isonicotinic acid hydrazide hydrochloride starting from 2-ethyl-6-methyl-isonicotinic acid; 1H NMR S 1.46 (t, J=7.6 Hz, 3H), 2.87 (s, 3H), 3.15 (q, J=7.6 Hz, 3H), 8.14 (s, 1H), 8.16 (s, 1H).

Sources & evidence

ORD record
ord-fc9946134fc048bfabb64b78569d0d00
Source dataset
uspto-grants-2013_12
Patent number
US08598208B2

Reaction notes

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