HCID 86661406, compound → (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid

Participants

Reaction Steps

58 mg of (R)-benzyl 3-(t-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoate, 3 mL of methanol, and 20 mg of 10 wt % palladium/carbon were added to 25 mL flask and the resulting reaction solution was stirred. A hydrogen gas was bubbled for 2 hours at room temperature; the reaction solution was filtered by passing through celite, washed with 15 mL of ethyl acetate, and the filtrate was concentrated under reduced pressure to obtain 44 mg of a title compound.

Provenance & Evidence