Phenyl chloroformate → HCID 58442676, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of isoxazolo[5,4-c]pyridin-3-ylamine (1.49 g, 11.0 mmol) in CH3CN (50 mL) was added phenyl chloroformate (0.696 mL, 5.50 mmol). The reaction mixture was heated at 70° C. overnight, then cooled to rt, diluted with H2O (100 mL) and saturated aqueous NaHCO3 (10 mL). The resulting yellow precipitate was filtered and dried under vacuum to give isoxazolo[5,4-c]pyridin-3-yl-carbamic acid phenyl ester (1.099 g, 39%). MS (ESI+): calcd for C13H9N3O3 m/z 255.06, found 256.1 (M+H)+.

Provenance & Evidence