HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68351212, compound → HCID 68351184, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68351212 | HCID 68351212 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Palladium | HCID 23938 | — |
| Product | HCID 68351184 | HCID 68351184 | 75.2% |
Reaction Steps
To a stirred solution of ethyl 6-(1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (0.45 g, 1.086 mmol) in EtOH (10 mL), 10% Pd/C in catalytic amount was added and stirred it at room temperature under hydrogen pressure (bladder pressure) for 3 hr. On completion of reaction, reaction mass was filtered through celite bed, then filtrate was concentrated under reduce pressure to give the desired compound (0.34 g, 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598167B1 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-82d2e04c0e8e412291d32ae6153c4130 |
| Source note | uspto-grants-2013_12 |