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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1909373Generated: November 1, 2026

2-[(2R)-oxolan-2-yl]acetic acid → HCID 178520757, compound

https://huagongshe.com/reaction/1909373

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[(2R)-oxolan-2-yl]acetic acidHCID 7201081—
ReactantHCID 178479251HCID 178479251—
ProductHCID 178520757HCID 178520757—

Reaction Steps

The title compound, off-white solid (34 mg, 62%), MS (ISP) m/z=443.5 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexylamine hydrochloride (intermediate A) (50 mg, 0.124 mmol) and (R)-2-(tetrahydrofuran-2-yl)acetic acid

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598357B2
Source datasetuspto-grants-2013_12
ORD IDord-b61f463a6ec0481c8422ac2ab9d37b98
Source noteuspto-grants-2013_12