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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1909395Generated: November 1, 2026

(2S)-3,3,3-trifluoro-2-hydroxypropanoic acid → HCID 178523626, compound

https://huagongshe.com/reaction/1909395

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-3,3,3-trifluoro-2-hydroxypropanoic acidHCID 7457723—
ReactantHCID 178479251HCID 178479251—
ProductHCID 178523626HCID 178523626—

Reaction Steps

The title compound, white solid (14.7 mg, 47.3%), MS (ISP) m/z=457.2 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexylamine hydrochloride (intermediate A) (25 mg, 0.0681 mmol) and (S)-3,3,3-trifluoro-2-hydroxypropanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598357B2
Source datasetuspto-grants-2013_12
ORD IDord-f8f1aca80fe541a69f97cb4a550e3592
Source noteuspto-grants-2013_12