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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1909396Generated: October 30, 2026

(2R)-3,3,3-Trifluoro-2-hydroxypropanoic acid → HCID 178523625, compound

https://huagongshe.com/reaction/1909396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-3,3,3-Trifluoro-2-hydroxypropanoic acidHCID 2779069—
ReactantHCID 178479251HCID 178479251—
ProductHCID 178523625HCID 178523625—

Reaction Steps

The title compound, white solid (17 mg, 54.7%), MS (ISP) m/z=457.2 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexylamine hydrochloride (intermediate A) (25 mg, 0.0681 mmol) and (R)-3,3,3-trifluoro-2-hydroxypropanoic acid

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598357B2
Source datasetuspto-grants-2013_12
ORD IDord-98e75fd9c421455fa57ae44b588b5b18
Source noteuspto-grants-2013_12