Tetrahydropyran-4-ylacetic acid → HCID 178520325, compound

Participants

Reaction Steps

The title compound, white solid (29.3 mg, 78.5%), MS (ISP) m/z=457.3 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexylamine hydrochloride (intermediate A) (30 mg, 0.0818 mmol) and 2-(tetrahydro-2H-pyran-4-yl)acetic acid.

Provenance & Evidence