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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1909414Generated: October 31, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178520183, compound

https://huagongshe.com/reaction/1909414

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReactantHCID 178479251HCID 178479251—
ProductHCID 178520183HCID 178520183—

Reaction Steps

The title compound, white solid (21.8 mg, 54.1%), MS (ISP) m/z=493.3 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexylamine hydrochloride (intermediate A) (30 mg, 0.0818 mmol) and 2-(benzo[d][1,3]dioxol-5-yl)acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598357B2
Source datasetuspto-grants-2013_12
ORD IDord-8c1c91fb60cd43b8a4b3af8660136e28
Source noteuspto-grants-2013_12