HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminosalicylic Acid → HCID 9926415, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminosalicylic Acid | HCID 4075 | — |
| Reactant | 4-Nitrophenethyl bromide | HCID 79266 | — |
| Product | HCID 9926415 | HCID 9926415 | 90.3% |
Reaction Steps
According to the similar procedure to Synthesis Example 1, by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-nitrophenylethyl bromide (900 mg, 3.92 mmole), 890 mg (50% yield) of 2-hydroxy-5-[2-(4-nitrophenyl)ethylamino]-benzoic acid was obtained as a pale yellow solid. Melting point 234-236° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598383B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-b59db2220c194d64bd49f788d7de1e00 |
| Source note | uspto-grants-2013_12 |