HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylallyl 2,3-difluoro-6-(2-methylallyloxy)benzoate → 2-Methylallyl 2,3-difluoro-6-hydroxy-5-(2-methylallyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylallyl 2,3-difluoro-6-(2-methylallyloxy)benzoate | HCID 58566703 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | 2-Methylallyl 2,3-difluoro-6-hydroxy-5-(2-methylallyl)benzoate | HCID 58566392 | 200% |
Reaction Steps
A solution of 2-methylallyl 2,3-difluoro-6-(2-methylallyloxy)benzoate (733) (1.53 g, 5.42 mmol) in NMP (3.5 mL) was heated in the microwave at 200° C. for 6 h. The solvent was removed in vacuo to provide 2-methylallyl 2,3-difluoro-6-hydroxy-5-(2-methylallyl)benzoate (734) (1.53 g) which was directly used in the next step reaction without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598374B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-f0538454a1214353bfb3cdcbad8b477a |
| Source note | uspto-grants-2013_12 |