HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → 4-(4-hydroxyphenoxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 4-(4-methoxyphenoxy)benzonitrile | HCID 1490279 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(4-hydroxyphenoxy)benzonitrile | HCID 4522712 | 74.4% |
Reaction Steps
Following the general procedure for Example 11 (step 2), boron tribromide (1.0 M solution in dichloromethane, 5.73 mL, 5.73 mmol) was added to the product from step 1 (0.43 g, 1.91 mmol) in dichloromethane (10 mL) to afford the title compound (0.30 g, 74%) as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598359B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-4d58eeab11d94a2ab87376dc0eef6f03 |
| Source note | uspto-grants-2013_12 |