Hydrochloric Acid → HCID 69001619, compound

Participants

Reaction Steps

Following the general procedure for Example 11 (step 4), the product from step 1 (0.41 g, 0.94 mmol) was treated with 4M HCl in dioxane (5 mL) to afford the title compound (0.22 g, 70%); 1H NMR (400 MHz, DMSO-d6) δ 1.76 (m, 1H), 1.95 (m, 2H), 2.13 (m, 1H), 3.23 (m, 2H), 3.90 (m, 1H), 4.17 (m, 1H), 4.26 (dd, J1=3.6 Hz, J2=10.4 Hz, 1H), 7.05-7.16 (m, 6H), 7.72 (d, J=8.4 Hz, 2H); MS (m/z) 338.5 (M+1); LC (99.1%); HPLC (99.4%).

Provenance & Evidence