Hydrochloric Acid → HCID 59753058, compound

Participants

Reaction Steps

To the product from step 1 (155 mg, 0.421 mmol) was added 4M HCl in dioxane (6 mL) and the resulting mixture was stirred at rt for 2 h. The solvent was removed in vacuo to obtain the title product as a solid (104 mg, 72%); MS; m/z 268 (M+H): LCMS (UV) 99%; 1H NMR (400 MHz, CD3OD) δ 1.86-1.96 (m, 1H), 2.06-2.18 (m, 2H), 2.23-2.31 (m, 1H), 3.32-3.39 (m, 2H), 3.99-4.12 (m, 2H), 4.30-4.33 (m, 1H), 6.92-7.01 (m, 3H), 7.07 (d, 2H, J=7.6 Hz), 7.16 (d, 2H, J=8.4 Hz); 7.26 (t, 2H, J=15.2 Hz)

Provenance & Evidence