HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-(Benzyloxy)phenyl)pyridine → Phenol, 4-(3-pyridinyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-(Benzyloxy)phenyl)pyridine | HCID 67226949 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran ethanol | HCID 21873804 | — |
| Product | Phenol, 4-(3-pyridinyl)- | HCID 153040 | 93% |
Reaction Steps
3-(4-Benzyloxy-phenyl)-pyridine (1.15 g, 4.4 mmol) in EtOH/THF (10 mL/25 mL) was treated with 10% Pd on carbon (1.5 g) over period of 48 h at rt under H 2 balloon. Reaction mixture was filtered through Celite and concentrated to obtain the product (700 mg, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598359B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-debc086b9e5e41cbad2a282dcdd42990 |
| Source note | uspto-grants-2013_12 |