Dimethyl Sulfoxide → Methyl 4-fluoro-2-(6-nitropyridin-3-yloxy)benzoate

HRID 190976Notes

Reaction equation

HRID 190976 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH3:29][S:30](=[O:31])[CH3:32].[Cl:13][c:14]1[cH:15][cH:16][c:17]([N+:20](=[O:21])[O-:22])[n:18][cH:19]1.[F:1][c:2]1[cH:3][c:4]([OH:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[K+:27].[K+:28].[OH2:33]>>[F:1][c:2]1[cH:3][c:4]([O:12][c:14]2[cH:15][cH:16][c:17]([N+:20](=[O:21])[O-:22])[n:18][cH:19]2)[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 2598065-Chloro-2-nitropyridineHCID 2775386Methyl 4-fluorosalicylate

Product 1

HCID 67226297Methyl 4-fluoro-2-(6-nitropyridin-3-yloxy)benzoate

Sources & evidence

ORD record
ord-3fd9b0240f1f452c9cf92993b2f75ab0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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