HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 6-Chloronicotinoyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6-Chloronicotinic acid | HCID 79222 | — |
| Product | 6-Chloronicotinoyl Chloride | HCID 2782165 | 89% |
Reaction Steps
6-Chloro-nicotinic acid (1.0 g, 6.34 mmol) was dissolved in 10 mL thionyl chloride and the resulting mixture was refluxed for 3 h. The excess thionyl chloride was removed under reduced pressure to give the title compound (1.0 g, 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598359B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-8cbaee5c990e4a5fafb569fbfa8afdcf |
| Source note | uspto-grants-2013_12 |