Hydrochloric Acid → HCID 59753039, compound

Participants

Reaction Steps

The title compound (15 mg, 80%) was prepared from the product of step 1 (20 mg, 0.05 mmol) and 4M HCl in dioxane (0.12 ml, 0.5 mmol) using the procedure of Example 146, step 4; 1HNMR (400 MHz, CD3OD) δ 8.0 (s, 1H), 7.93 (d, J=38.4 Hz, 2H), 7.34 (d, s, J=8.4 Hz, 3H), 7.19 (d, J=8.8 Hz, 2H), 6.95 (d, J=8.8 Hz, 2H), 4.32 (dd, J=10.4, 3.6 Hz, 1H), 4.10 (m, 1H), 4.32 (m, 2H), 4.10 (m, 1H), 3.94 (s, 2H), 3.36 (m, 2H), 2.25 (m, 1H), 2.10 (m, 2H), 1.90 (m, 1H); LC/MS (APCI+) 90%, 335 (M+1, 100).

Provenance & Evidence