HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromothiophene-2-carbaldehyde → 5-(4-methoxyphenyl)thiophene-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromothiophene-2-carbaldehyde | HCID 78428 | — |
| Reactant | (4-Methoxyphenyl)boronic acid | HCID 201262 | — |
| Product | 5-(4-methoxyphenyl)thiophene-2-carbaldehyde | HCID 2797800 | 82% |
Reaction Steps
The title compound was prepared from 5-bromo-thiophene-2-carbaldehyde (2.0 g, 10.5 mmol) and (4-methoxyphenyl) boronic acid (1.6 g, 11 mmol) using the procedure of Example 159, step 1 with 82% yield (1.9 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598359B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-528d8db124894b02a0576e5c5475ad84 |
| Source note | uspto-grants-2013_12 |