HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Methoxyisoquinoline-3-carboxylic acid → 3-Isoquinolinecarboxylic acid, 7-methoxy-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-Methoxyisoquinoline-3-carboxylic acid | HCID 57306949 | — |
| Edukt | Boc-7-hydroxy-tetrahydroisoquinoline carboxylic acid | HCID 66940410 | — |
| Produkt | 3-Isoquinolinecarboxylic acid, 7-methoxy- | HCID 10822014 | 17% |
Reaktionsschritte
0.25 g (17% in 4 steps) 7-methoxy-isoquinoline-3-carboxylic acid was prepared according to procedure described for the synthesis of 6-methoxy-isoquinoline-3-carboxylic acid (in Example 294) starting from 2.0 g (6.8 mmol) of boc-7-hydroxy-tetrahydroisoquinoline carboxylic acid using 179 mg (0.824 mmol). LCMS: 204 (M+1)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08598353B2 |
| Quelldatensatz | uspto-grants-2013_12 |
| ORD ID | ord-f715c9a3a13e4cd68193a6af34ab6178 |
| Quellennotiz | uspto-grants-2013_12 |