HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanogen Bromide → HCID 66940552, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Reactant | 106976-20-9 | HCID 13792245 | — |
| Reactant | methyl 2-amino-1H-benzo[d]imidazole-4-carboxylate | HCID 24730367 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66940552 | HCID 66940552 | — |
Reaction Steps
0.9 g (4.9 mmol) of 2,3-diamino-4-methoxy-benzoic acid was subjected to a similar cyclization condition as illustrated in intermediate A by using 2.6 g (24.5 mmol) of BrCN in methanol to produce 2-amino-7-methoxy-1H-benzoimidazole-4-carboxylic acid. LCMS: 208 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598353B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-cd4d3c0be5334f76b5f11993ba2670b9 |
| Source note | uspto-grants-2013_12 |