1,3-Propanediamine → HCID 71548937, compound

Participants

Reaction Steps

The title compound was prepared in analogy to Example 1-1 in Scheme 1 by using 2,4-dichlorothieno[3,2-d]pyrimidine and propane-1,3-diamine, followed by reaction with 2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine. MS obsd. (ESI+) [(M+H)+] 356, 1H NMR (400 MHz, METHANOL-d4) δ ppm 7.72 (d, J=5.3 Hz, 1H), 7.43 (d, J=7.1 Hz, 1H), 7.12-7.18 (m, 1H), 7.08 (d, J=5.6 Hz, 1H), 6.93-7.04 (m, 2H), 4.93 (s, 2H), 4.20-4.26 (m, 2H), 4.14-4.19 (m, 2H), 3.71 (t, J=6.4 Hz, 2H), 2.88 (t, J=7.5 Hz, 2H), 1.96 (m, 2H).

Provenance & Evidence