Thionyl Chloride → 2-Hydroxy-4-nitrobenzoyl chloride

Beteiligte Stoffe

Reaktionsschritte

Thionyl chloride (1.6 mL, 22 mmol) was added slowly to a solution of 4-nitrosalicylic acid (1.0 g, 5.46 mmol) in chloroform (20 mL) at 0° C. The mixture was brought to reflux and maintained for 5 h. Excess thionyl chloride was evaporated to give 2-hydroxy-4-nitro-benzoyl chloride (0.82 g, 75%).

Herkunft & Nachweise