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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1911506Generated: November 4, 2026

Cyanogen Bromide → (S)-4-(2-phenyl-propyl)-4,5-dihydro-oxazol-2-ylamine

https://huagongshe.com/reaction/1911506

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyanogen BromideHCID 10476—
Reactant(S)-2-amino-4-phenyl-pentan-1-olHCID 68709718—
Product(S)-4-(2-phenyl-propyl)-4,5-dihydro-oxazol-2-ylamineHCID 59323620—

Reaction Steps

In analogy to example 1b (S)-2-amino-4-phenyl-pentan-1-ol was reacted with cyanogen bromide to give (S)-4-(2-phenyl-propyl)-4,5-dihydro-oxazol-2-ylamine. Off-white waxy solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08604061B2
Source datasetuspto-grants-2013_12
ORD IDord-29b2be5a3e5240098e2468fcaebcd4a9
Source noteuspto-grants-2013_12