HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-amino-2-(4-chlorophenyl)propanoic Acid → HCID 59323796, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-amino-2-(4-chlorophenyl)propanoic Acid | HCID 3847762 | — |
| Reactant | HCID 65583628 | HCID 65583628 | — |
| Product | HCID 59323796 | HCID 59323796 | — |
Reaction Steps
In analogy to example 126 (RS)-2-amino-2-(4-chloro-phenyl)-propionic acid was converted to (RS)-4-(4-chloro-phenyl)-4-methyl-4,5-dihydro-oxazol-2-ylamine which was subsequently separated by chiral HPLC (Chiralpak AD, EtOH/heptane 15:85) to give (S)-4-(4-chloro-phenyl)-4-methyl-4,5-dihydro-oxazol-2-ylamine. Off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604061B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-6ba4dfa0525840f8befab87aae30a1ed |
| Source note | uspto-grants-2013_12 |