HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanogen Bromide → (S)-4-(1-methyl-2-phenyl-ethyl)-4,5-dihydro-oxazol-2-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Reactant | (S)-2-amino-3-methyl-4-phenyl-butan-1-ol | HCID 68716469 | — |
| Product | (S)-4-(1-methyl-2-phenyl-ethyl)-4,5-dihydro-oxazol-2-ylamine | HCID 24968258 | — |
Reaction Steps
In analogy to example 1b (S)-2-amino-3-methyl-4-phenyl-butan-1-ol was reacted with cyanogen bromide to give (S)-4-(1-methyl-2-phenyl-ethyl)-4,5-dihydro-oxazol-2-ylamine. Off-white amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604061B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-5e64e08352ff4a57946ae864f535d5fc |
| Source note | uspto-grants-2013_12 |