HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Butanol → Butyl ethyl-3-hydroxypropylphosphinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Butanol | HCID 263 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Ethyl-3-hydroxypropylphosphinic acid | HCID 86656674 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Butyl ethyl-3-hydroxypropylphosphinate | HCID 86656676 | 84% |
Reaction Steps
456 g (3 mol) of ethyl-3-hydroxypropylphosphinic acid (produced as in Example 10) are at 85° C. dissolved in 400 ml of toluene and admixed with 888 g (12 mol) of butanol. At a reaction temperature of about 100° C., the water formed is removed by azeotropic distillation to obtain 524 g (84% of theory) of butyl ethyl(3-hydroxy-propyl)phosphinate purified by distillation at reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604108B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-09a989863c8941fca2ff5d55b324298d |
| Source note | uspto-grants-2013_12 |