反应详情

A 500 ml five-neck flask equipped with gas inlet tube, thermometer, high-performance stirrer and reflux condenser with gas incineration is charged with 152 g (1 mol) of ethyl(3-hydroxypropyl)phosphinic acid (produced similarly to Example 13). Ethylene oxide is passed in at room temperature. A reaction temperature of 70° C. is set with cooling, followed by further reaction at 80° C. for 1 hour. The ethylene oxide takeup is 64.8 g. The acid number of the product is less than 1 mg KOH/g. 186 g (95% of theory) of 2-hydroxyethyl ethyl(3-hydroxy-propyl)phosphinate are obtained as colorless, water-clear liquid.

1. customA 500 ml five-neck flask equipped with gas inlet tube
2. temperaturethermometer, high-performance stirrer and reflux condenser with gas incineration
3. customproduced similarly to Example 13)
4. customis passed in at room temperature
5. customA reaction temperature of 70° C.
6. temperaturewith cooling
7. customfollowed by further reaction at 80° C. for 1 hour