1-BOC-3-Aminopiperidine → HCID 59799770, compound

HRID 1911905Notes

Reaction equation

HRID 1911905 reaction equation
Br[C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[N:8]([CH2:11][C:12]3[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=3)[CH:9]=[CH:10][C:3]=12.[C:20]([O:24][C:25]([N:27]1[CH2:32][CH2:31][CH2:30][CH:29]([NH2:33])[CH2:28]1)=[O:26])([CH3:23])([CH3:22])[CH3:21]>>[CH3:19][O:18][C:15]1[CH:16]=[CH:17][C:12]([CH2:11][N:8]2[C:4]3=[N:5][CH:6]=[CH:7][C:2]([NH:33][CH:29]4[CH2:30][CH2:31][CH2:32][N:27]([C:25]([O:24][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:26])[CH2:28]4)=[C:3]3[CH:10]=[CH:9]2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 5458091-BOC-3-AminopiperidineHCID 59799773HCID 59799773, compound

Product 1

HCID 59799770HCID 59799770, compound

Procedure

Reaction of 4-bromo-1-(4-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine with tert-butyl3-aminopiperidine-1-carboxylate following the method of Example 13 affords the title compound.

Sources & evidence

ORD record
ord-ba27ff55d3eb4aae970b6619117826a8
Source dataset
uspto-grants-2013_12
Patent number
US08604205B2

Reaction notes

Loading…