1-Bromo-4-chlorobutane → HCID 71529608, compound
Reaction equation
[OH:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.Br[CH2:12][CH2:13][CH2:14][CH2:15][Cl:16]>>[Cl:16][CH2:15][CH2:14][CH2:13][CH2:12][O:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1Participants
3
Procedure
2-hydroxybenzothiazole (0.2 g, 1.32 mmol) and 1-bromo-4-chlorobutane (0.227 g, 1.32 mmol) were reacted in the same manner as in Example 1 to afford the compound K24 (0.302 g, 94%).
Workup
- customto afford the compound K24 (0.302 g, 94%)
Sources & evidence
- ORD record
- ord-3949e6c8debd485dbd784861a366695e
- Source dataset
- uspto-grants-2013_12
- Patent number
- US08604214B2
Reaction notes
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