Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-Ethylaniline | HCID 7670 | — |
| Reactant | 2-Methoxyethanol | HCID 8019 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-Chlorocyclohexanone | HCID 13203 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 524499 | HCID 524499 | 24.2% |
Reaction Steps
132.5 g of 2-chloro-cyclohexanone was added to 123.42 g of N-ethyl aniline, 500 ml of methyl cellosolve, 127 g of dry sodium carbonate and 7.9 g of pyridine at 30-40° C. over a period of 1 hour. Reaction mass was heated to 100° C. and stirred for 2 hours. Reaction temperature was further raised to 130° C. and held at this temperature till no more water get distilled. Reaction mass was then worked up to get 48.2 g of crude 9-ethyl-tetrahydrocarbazole of 96.3% GC purity.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08604219B2 |
|---|
| Source dataset | uspto-grants-2013_12 |
|---|
| ORD ID | ord-50d9e8810bc24b3ba7e7a2ea1bc38fde |
|---|
| Source note | uspto-grants-2013_12 |
|---|
