HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-fluoro-4-oxo-4H-chromene-2-carboxylic acid → 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-fluoro-4-oxo-4H-chromene-2-carboxylic acid | HCID 4096046 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid | HCID 15382843 | — |
Reaction Steps
6-Fluoro-4-oxo-4H-1-benzopyran-2-carboxylic acid (III) was reacted with 10% palladium on carbon in acetic acid as solvent under hydrogen atmosphere to give 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid (IV) as shown in Reaction-2 given below by a known process (U.S. Pat. No. 4,654,362).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604222B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-5649e2659df24f9cb36245c3819c6e14 |
| Source note | uspto-grants-2013_12 |