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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1911992Generated: November 1, 2026

Tert-butyl 3-oxopyrrolidine-1-carboxylate → 2,2-Dimethyl-1-(5-(pyrrolidin-3-ylamino)-1H-indazol-1-yl)propan-1-one

https://huagongshe.com/reaction/1911992

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 3-oxopyrrolidine-1-carboxylateHCID 471360—
ReactantHCID 66716091HCID 66716091—
Product2,2-Dimethyl-1-(5-(pyrrolidin-3-ylamino)-1H-indazol-1-yl)propan-1-oneHCID 59799779—

Reaction Steps

Reaction of tert-butyl 3-oxopyrrolidine-1-carboxylate and 1-(5-amino-1H-indazol-1-yl)-2,2-dimethylpropan-1-one maleate salt using the method of Example 3 followed by deprotection using the method of Example 4 afforded the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08604218B2
Source datasetuspto-grants-2013_12
ORD IDord-da76bfbeafed4a90bb15a3589f2782fe
Source noteuspto-grants-2013_12