HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminoisoquinoline → N-(Pyrrolidin-3-yl)isoquinolin-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminoisoquinoline | HCID 70766 | — |
| Reactant | Tert-butyl 3-oxopyrrolidine-1-carboxylate | HCID 471360 | — |
| Product | N-(Pyrrolidin-3-yl)isoquinolin-5-amine | HCID 57936477 | — |
Reaction Steps
Reaction of tert-butyl 3-oxopyrrolidine-1-carboxylate and isoquinolin-5-amine using the method of Example 3 followed by deprotection using the method of Example 4 afforded the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604218B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-8e653726e32c459e83d4b22605986e88 |
| Source note | uspto-grants-2013_12 |