1-BOC-3-Aminopiperidine → HCID 59799770, compound

HRID 1912013Notes

Reaction equation

HRID 1912013 reaction equation
Br[C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[N:8]([CH2:11][C:12]3[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=3)[CH:9]=[CH:10][C:3]=12.[NH2:20][CH:21]1[CH2:26][CH2:25][CH2:24][N:23]([C:27]([O:29][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:28])[CH2:22]1>>[CH3:19][O:18][C:15]1[CH:16]=[CH:17][C:12]([CH2:11][N:8]2[C:4]3=[N:5][CH:6]=[CH:7][C:2]([NH:20][CH:21]4[CH2:26][CH2:25][CH2:24][N:23]([C:27]([O:29][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:28])[CH2:22]4)=[C:3]3[CH:10]=[CH:9]2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 5458091-BOC-3-AminopiperidineHCID 59799773HCID 59799773, compound

Product 1

HCID 59799770HCID 59799770, compound

Procedure

Reaction of 4-bromo-1-(4-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine with tert-butyl 3-aminopiperidine-1-carboxylate following the method of Example 13 affords the title compound.

Sources & evidence

ORD record
ord-d3c79d7be3ab4430bdbf5806fffe8df4
Source dataset
uspto-grants-2013_12
Patent number
US08604218B2

Reaction notes

Loading…