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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912020Generated: November 3, 2026

Benzaldehyde, 3-(2-hydroxyethoxy)- → 2-(3-((3-(Isoquinolin-5-ylamino)pyrrolidin-1-yl)methyl)phenoxy)ethanol

https://huagongshe.com/reaction/1912020

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehyde, 3-(2-hydroxyethoxy)-HCID 6453965—
ReactantN-(Pyrrolidin-3-yl)isoquinolin-5-amineHCID 57936477—
Product2-(3-((3-(Isoquinolin-5-ylamino)pyrrolidin-1-yl)methyl)phenoxy)ethanolHCID 25008327—

Reaction Steps

Reaction of N-(pyrrolidin-3-yl)isoquinolin-5-amine with 3-(2-hydroxyethoxy)benzaldehyde using the method of Example 8 afforded the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08604218B2
Source datasetuspto-grants-2013_12
ORD IDord-b1024cba13bd4ef29222800a869d9146
Source noteuspto-grants-2013_12