反应详情

414 g (2 mol) of butyl ethyl(3-aminopropyl)phosphinate (produced as in Example 6) are initially charged to a 1 l five-neck flask equipped with thermometer, reflux condenser, high-performance stirrer and dropping funnel. At 160° C., during 4 h, 500 ml of water are metered in and a butanol-water mixture is distilled off. The solid residue is recrystallized from acetone to obtain 296 g (98% of theory) of ethyl(3-aminopropyl)phosphinic acid as colorless solid.

1. customequipped with thermometer
2. temperaturereflux condenser, high-performance stirrer
3. distillationis distilled off
4. customThe solid residue is recrystallized from acetone