Ethylene Glycol → 2-Hydroxyethyl ethyl(3-aminopropyl)phosphinate

HRID 1912023Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1912023
[CH2:1]([P:3]([CH2:10][CH2:11][CH2:12][NH2:13])(=[O:9])[O:4][CH2:5][CH2:6]CC)[CH3:2].C(O)C[OH:16]>C(O)(C([O-])=O)=O.C(O)(C([O-])=O)=O.O.O=[Ti].[K+].[K+]>[CH2:1]([P:3]([CH2:10][CH2:11][CH2:12][NH2:13])(=[O:9])[O:4][CH2:5][CH2:6][OH:16])[CH3:2]

Komponenten

4

Edukt 2

HCID 174Ethylene GlycolHCID 46212699Butyl ethyl(3-aminopropyl)phosphinate

Produkt 1

HCID 462127002-Hydroxyethyl ethyl(3-aminopropyl)phosphinateAusbeute 96 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 91886499Dipotassium;bis(2-hydroxy-2-oxoacetate);oxotitanium;hydrateKatalysator

Reaktionsbedingungen

Temperatur
200 °C

Versuchsvorschrift

To 414 g (2 mol) of butyl ethyl(3-aminopropyl)phosphinate (produced as in Example 6) are added 155 g (2.5 mol) of ethylene glycol and 0.4 g of potassium titanyl oxalate followed by stirring at 200° C. for 2 h. Volatiles are distilled off by gradual evacuating to leave 374 g (96% of theory) of 2-hydroxyethyl ethyl(3-aminopropyl)phosphinate.

Aufarbeitung

  1. distillationVolatiles are distilled off
  2. customby gradual evacuating

Quellen und Nachweise

ORD-Eintrag
ord-25b0846b94fa4278b078a1b60104ced3
Quelldatensatz
uspto-grants-2013_12
Patentnummer
US08604232B2

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