HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1,3,3-Tetramethyl-disiloxane → 1-(4-Methyl-1-pentenyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1,3,3-Tetramethyl-disiloxane | HCID 18659 | — |
| Reactant | 4-Methyl-1-(piperidin-1-YL)pentan-1-one | HCID 22980873 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(4-Methyl-1-pentenyl)piperidine | HCID 86675030 | 248.3% |
Reaction Steps
4-Methyl-1-piperidin-1-ylpentan-1-one (372.4 g) and toluene (1000 mL) were mixed. To the mixture was added (Ph3P)IrCl(CO) (633 mg). In a water-bath, 1,1,3,3-tetramethyldisiloxane (627 mL) was added dropwise to the mixture. The resulting mixture was stirred at RT for 2 hr. The reaction mixture was concentrated in vacuo to give the title compound (844 g) as a crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604069B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-356f1af117b84067a3e5097a7db678d9 |
| Source note | uspto-grants-2013_12 |