HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912064Generated: October 26, 2026
Hydroquinone → Ethyl 3-(2,2-dimethylpropyl)-2-piperidin-1-ylcyclobutanecarboxylate
https://huagongshe.com/reaction/1912064
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydroquinone | HCID 785 | — |
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Reactant | 1-(4,4-Dimethyl-1-pentenyl)piperidine | HCID 86675037 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Ethyl 3-(2,2-dimethylpropyl)-2-piperidin-1-ylcyclobutanecarboxylate | HCID 71114785 | — |
Reaction Steps
1-(4,4-Dimethyl-1-pentenyl)piperidine (1146 g) and acetonitrile (910 mL) were mixed. After an addition of ethyl acrylate (549 mL) and hydroquinone (553 mg) to the mixture, the mixture was stirred at 90° C. overnight. The reaction mixture was concentrated in vacuo to give the title compound (1470 g) as a crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08604069B2 |
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| Source dataset | uspto-grants-2013_12 |
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| ORD ID | ord-11adb3d2d20e4c44a3a8e3c23eebcdf5 |
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| Source note | uspto-grants-2013_12 |
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