HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroquinone → Ethyl 3-(2-ethylbutyl)-2-piperidin-1-ylcyclobutanecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroquinone | HCID 785 | — |
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Reactant | 1-(4-Ethyl-1-hexenyl)piperidine | HCID 86675047 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Ethyl 3-(2-ethylbutyl)-2-piperidin-1-ylcyclobutanecarboxylate | HCID 71114773 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
1-(4-Ethyl-1-hexenyl)piperidine (98.1 g) and acetonitrile (70 mL) were mixed. To the mixture were added ethyl acrylate (53.0 mL) and hydroquinone (271 mg). The mixture was stirred at 100° C. overnight. The reaction mixture was concentrated in vacuo to give the title compound (132 g) as a crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604069B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-25fb591a9cb744e1852c6ef39919250a |
| Source note | uspto-grants-2013_12 |