Trifluoroacetic acid → HCID 71114719, compound

Participants

Reaction Steps

tert-Butyl 3-[5-cyclopropyl-1-(3-isobutylcyclobutyl)-1H-[1,2,3]triazol-4-yl]-4-(2,4-dimethylphenylcarbamoyl)butyrate (100 mg) and chloroform (0.8 mL) were mixed. To the mixture was added trifluoroacetic acid (0.2 mL) at ice temperature. After stirring at RT for 6 hr, the reaction mixture was concentrated in vacuo. The resultant residue was purified by preparative chromatography (Eluent: chloroform/methanol/acetic acid=20/1/0.1) to give the title compound (79.5 mg).

Provenance & Evidence