Dimethylcarbamoyl Chloride → HCID 86652108, compound

Participants

Reaction Conditions

Reaction Steps

15.0 g (139.5 mmol) of N,N-dimethylcarbamoyl chloride and 80 mL dioxane were added to a 250 mL two-necked flask with a reflux condenser. Then 13.66 g (135 mmol) triethylamine and 10.44 g (139 mmol) of 3-amino-1-propanol were added. After exothermic evolution of heat subsided, the mixture was stirred for 1 h at 60° C. and for 3 h at 90° C., where a light brown suspension slowly formed. After the suspension had been cooled down to 50° C., the solid was filtered out.

Provenance & Evidence