Urea → HCID 131731081, compound

Participants

Reaction Conditions

Reaction Steps

15.0 g (139.5 mmol) of N,N-dimethylcarbamoyl chloride and 80 mL dioxane were added to a 250 mL two-necked flask with a reflux condenser. Then 13.66 g (135 mmol) triethylamine and 14.88 g (approx. 63 mmol) Jeffamine® D-230 (Huntsman) were added. After the slight exothermic evolution of heat subsided, the mixture was stirred for 3 h at 80° C. and for 1 h at 100° C., where a milky yellowish suspension slowly formed. The suspension obtained in this way was filtered twice through a fluted filter. The solvent was driven off on the rotary evaporator at 60° C. Then the product was purified with stirring for 2 h at 100° C. and 0.3 mbar. Approximately 17.0 g of an orange-red, viscous liquid was obtained, with a calculated “urea equivalent weight” of approx. 191 g/eq.

Provenance & Evidence