Dimethylcarbamoyl Chloride → HCID 86652109, compound

Participants

Reaction Conditions

Reaction Steps

9.07 g (46.5 mmol) of tyrosine methyl ester and 50 mL dioxane were weighed out into a 250 mL two-necked flask. Then first 4.55 g (45.0 mmol) triethylamine and then 5.0 g (46.5 mmol) of N,N-dimethylcarbamoyl chloride were added. After the exothermic evolution of heat subsided, the mixture was stirred for 2 h at 70° C., where a yellowish, increasingly difficultly stirrable suspension slowly formed.

Provenance & Evidence