2-Azido-9-benzyl-6-bromo-9-azabicyclo[3.3.1]nonane → 2-Benzyl-2,7-diaza-tricyclo-[4.4.0.03,8]decane

Participants

Reaction Steps

The synthesis described in Ex. 2.1 was repeated, but substituting the azide (1.1A) with the compound (1.1B) obtained in Ex. 1.1. The compound 2-benzyl-2,7-diaza-tricyclo-[4.4.0.03,8]decane is obtained. Yield: 68%. 1H-NMR (CDCl3) δ 1.50-2.00 (m, 8H); 2.70-2.80 (m, 2H); 3.00-3.10 (m, 2H); 3.90 (AB system, 2H, J=13.8 Hz); 7.20-7.42 (m, 5H). Anal. calc. for C15H20N2: C, 78.90; H, 8.83; N, 12.27. Found: C, 78.78; H, 8.81; N, 12.26.

Provenance & Evidence