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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912344Generated: October 26, 2026

{4-[(10-Benzyl-9,10-diazatricyclo[4.2.1.12,5]-dec-9-yl)-(3-methoxyphenyl)methyl]phenyl}-piperidin-1-yl-methanone → {4-[(9,10-Diazatricyclo[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)-methyl]phenyl}-piperidin-1-yl-methanone

https://huagongshe.com/reaction/1912344

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{4-[(10-Benzyl-9,10-diazatricyclo[4.2.1.12,5]-dec-9-yl)-(3-methoxyphenyl)methyl]phenyl}-piperidin-1-yl-methanoneHCID 67237737—
Reactant4-[(10-benzyl-9,10-diazatricyclo-[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)methyl]-N,N-diethylbenzamideHCID 67238357—
Product{4-[(9,10-Diazatricyclo[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)-methyl]phenyl}-piperidin-1-yl-methanoneHCID 67238089—

Reaction Steps

The procedure of Example 5.1 was repeated, but using instead of the compound prepared in Example 4.1 the compound {4-[(10-benzyl-9,10-diazatricyclo[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)methyl]phenyl}-piperidin-1-yl-methanone of Example 4.3. The compound {4-[(9,10-diazatricyclo[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)-methyl]phenyl}-piperidin-1-yl-methanone was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609659B2
Source datasetuspto-grants-2013_12
ORD IDord-af3f39e8e4f44c77b72a28f9691d9185
Source noteuspto-grants-2013_12