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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912424Generated: October 31, 2026

Benzaldehyde → 2-(Benzylamino)propan-1-ol

https://huagongshe.com/reaction/1912424

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantL-AlaninolHCID 80307—
CatalystHCID 178418390HCID 178418390—
SolventEthanolHCID 702—
Product2-(Benzylamino)propan-1-olHCID 138873—

Reaction Steps

To a solution of (S)-(+)-2-aminopropan-1-ol (50.0 g) and benzaldehyde (74 ml) in ethanol (500 ml) was added 5% palladium carbon (5.0 g), and the mixture was hydrogenated at room temperature under ordinary pressure for 8 hours. The reaction mixture was filtered through Celite, and concentrated under reduced pressure to give the titled compound (111.2 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609647B2
Source datasetuspto-grants-2013_12
ORD IDord-ed3f2c5c5e194e6e80b399ab1d7263dc
Source noteuspto-grants-2013_12