tert-Butyl 7-benzyl-6-oxo-1,7-diazaspiro[4.5]decane-1-carboxylate → tert-Butyl 1,7-diazaspiro[4.5]decane-1-carboxylate

Participants

Reaction Steps

To a solution of 7-benzyl-6-oxo-1,7-diazaspiro[4.5]decane-1-carboxylic acid tert-butyl ester (76 mg) in tetrahydrofuran/methanol (1 ml/1 ml) was added 20% palladium hydroxide carbon (15 mg), and the mixture was hydrogenated under 4 atmospheres. The mixture was filtered through Celite under nitrogen, and the filtrate was concentrated under reduced pressure to give the titled compound (51 mg).

Provenance & Evidence