HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 44221300, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | Benzoic acid, 2-isothiocyanato-, methyl ester | HCID 85243 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 44221300 | HCID 44221300 | 94.6% |
Reaction Steps
Methyl 2-isothiocyanatobenzoate (Acros) (20.0 g, 104 mmol) was dissolved in tetrahydrofuran (300 mL), followed by addition of diethylamine (35.9 mL, 349 mmol). The reaction mixture was stirred at room temperature. After 1 hour, the mixture was poured into water (800 mL). The precipitate was collected by filtration, washed with water and dried under vacuum to give the title compound (26.2 g, yield 94.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609674B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-23b6ef7706a14d408d5c88c1e1181206 |
| Source note | uspto-grants-2013_12 |